Top 100 Drugs Of Choice For Different Diseases
Drugs of choice for different diseases are categorized on the basis of diseases. Following are the most important classes of drugs used as a first choice in the treatment of different diseases.
Drugs Of Choice List in pregnancy
(1)Chloroquine
- Drug of choice for malaria in pregnancy
(2) Alpha-Methyldopa
- Drug of choice for hypertension in pregnancy
(3) Femara
- For breast cancer.
(4) Labetalol
- For the hypertensive crisis in pregnant women.
(5) Acetaminophen
- Analgesic DOC
(6) Phenobarbitone
- For epilepsy in pregnant women.
(7) Doxylamine & Pyridoxine
- For nausea in pregnancy
Drugs Of Choice List in infections
(8) Penicillin G
Drug of choice in
- Septicemia,
- Meningitis,
- Pericarditis,
- Endocarditis and
- Severe pneumonia.
(9) Ampicillin
Drug of choice in
- Listeria,
- Enterococcus faecalis.
(10) Vancomycin
Drug of choice for
- MRSA,
- Coagulase-negative Staphylococcus,
- Enterococcus faecium.
(11) Erythromycin
Drug of choice for
- Corynebacterium
(12) Doxycycline
- Bacillus anthracis,
- Borrelia burgdorferi, B.Recurrentis.
- Chalmydia & Rickettsiae.
(13) Cotrimoxazole
Drug of choice in
- Nocardia
(14) Azithromycin
Drug of choice in
- Hemophilus ducreyi &
- Mycoplasma .
(15) Ceftriaxone
Drug of choice for
- Proteus,
- E.coli,
- Salmonella
Drug of choice for
- Urinary Tract Infection
(17) Metronidazole
Drug of choice for
- Bacteriocides
(18) Ceftazidime
DOC for
- Burkholderia pseudomallei
Drugs Of Choice List for various types of seizures
(19) Valproate
Drug of choice for
- Tonic seizures
- Absence seizures
- Grand mal (GTCS)
- Clonic seizures
- Atonic seizures
- Myoclonic seizures
(20) Carbamazepine
- Partial seizures
(21) Vigabatrin
- Infantile spasm with tuberous sclerosis
(22) ACTH
- Infantile spasm
(23) Lorazepam (IV)
- Status epilepticus
(24) Diazepam
- Febrile seizures
(25) Magnesium Sulphate
- Seizure in eclampsia
Drugs Of Choice List in poisoning
(26) Physostigmine
- Atropine,
- Belladonna &
- Dhatura poisoning
(27) Atropine
- Carbamate,
- Early mushroom poisoning,
- Organophosphate poisoning.
(28) Flumazenil
- Benzodiazepine poisoning
(29) Acetylcysteine
- Acetaminophen poisoning
(30) Naloxone
- Opioid poisoning
(31) Deferiprone
- Chronic iron poisoning
(32) Desferrioxamine
- Acute iron poisoning
(33) Glucagon
- Beta-blockers poisoning
(34) Amyl nitrate
- Cyanide poisoning
Drugs Of Choice List in bronchial asthma
(35) Salbutamol
Salbutamol is the drug of choice for
- An acute attack of bronchial asthma in normal patient and pregnant women.
- Exercise & Aspirin-induced acute attack of bronchial asthma.
(36) Ipratropium
- An acute attack of bronchial asthma during labor.
- An acute attack of bronchial asthma on beta-blocker therapy.
(37) Corticosteroids
- Prophylaxis of bronchial asthma,
- Exercise-induced, and
- Aspirin-induced asthma.
Drugs Of Choice List In Antimicrobials Prophylaxis
(38) Ampicillin
- Group B streptococcus infection
(39) Amoxicillin
- Endocarditis and Otitis media
(40) Azithromycin
- Mycobacterium avium complex (MAC) Pertussis
(41) Benzathine penicillin
- Rheumatic fever
(42) Procaine Penicillin
- Gonorrhea and syphilis
(43) Tetracycline
- Rickettsial infection and plague.
(44) Cefazoline
- Surgical Prophylaxis
(45) Doxycycline
- Anthrax
(46) Trimethoprim and sulphamethoxazole
- Toxoplasmosis,
- Pneumocystis service UTI
(47) Rifampicin
- Hemophilus influenza type B.
(48) Oseltamivir
- Influenza Type A & B.
Anesthetic Drugs Of Choice List
(49) Propofol
- Daycare
(50) Sevoflurane
- Congenital heart disease,
- ASD,VSD,PDA
(51) Etomidate
- Ischemic heart disease
(52) Ketamine
- Asthma and COPD
- Shock
- CHF, and
- congenital heart disease (Right to left shunt)
(53) Thiopentone
- Epilepsy
- Thyrotoxicosis
(54) Methohexitone
- Electroconvulsive therapy
(55) Isoflurane
- Cardiac surgery
- Neurosurgery
- For producing deliberate hypotension
Drugs Of Choice List in Endocrinological Disorders
(56) Insulin
- Type 1 DM
- Diabetes Mellitus in pregnancy.
- Diabetic Ketoacidosis.
- Uncontrolled DM.
(57) Metformin
- Type 2 DM
- Diabetes mellitus in obesity
(58) Sildenafil
- Erectile Dysfunction
(59) Hydrocortisone
- Acute and chronic adrenal insufficiency.
(60) Nateglinide
- Postprandial hyperglycemia.
(61) Methotrexate
- Ectopic pregnancy
(62) Oxytocin
- Postpartum hemorrhage
- Induction of labor
(63) Cabergoline
- Acromegaly
- Hyperprolactinemia.
(64) Finasteride
- Anogenital alopecia.
(65) Alendronate
- Osteoporosis
Drugs of choice in fungal infections
(66) Amphotericin B
Amphotericin B is the drug of choice in
- Meningeal histoplasmosis
- Endocarditis by candida
- Sever or CNS blastomycosis
- Induction cryptococcal meningitis(For 2 weeks)
- Exserohium
(67) Fluconazole
- Candida albicans
- Maintainance in cryptococcal meningitis
(68) itraconazole
- Nonmeningeal histoplasmosis
- Sporotrichosis
- Para Coccidioidomycosis
- Mild or non-CNS blastomycosis
- Chromoblastomycosis
- Penicillium mameffei
(69) Prednisolone+itraconazole/Voriconazole
- Allergic bronchopulmonary aspergillosis.
(70) Caspofungin
- Candida glabrate, and
- Candida krusei.
Drugs of choice in gastrointestinal disorders
(71) PPIs (Proton Pump Inhibitors)
- Gastric ulcer,
- Duodenal ulcer,
- stress ulcer,
- NSAIDs-induced ulcer.
- GERD,& Zollinger Ellison syndrome.
(72) Metoclopramide
- A migraine associated or drug or disease associated vomiting
(73) Domperidone
- Levodopa-induced vomiting
(74) Ondansetron
- Postoperative or radiation-induced vomiting
(75) 5HT3 antagonist
- Cisplatin-induced early vomiting
(76) Lactulose
- Hepatic encephalopathy
(77) Methylnaltrexone
- Opioid-induced constipation
(78) Octreotide
- Diarrhea in carcinoid syndrome
Drugs of choice in Hematological Disorders
(79) Warfarin
- DVT prophylaxis
- Chronic atrial fibrillation in mitral stenosis,
- Advanced kidney disease, and
- mechanical prosthetic heart valves
(80) Heparin+Warfarin
- Initiation of therapy in DVT.
(81) Vitamin K
- Warfarin overdose
(82) Protamine
- Heparin overdose
Drugs of Choice in Hypertension
(83) Thiazide diuretics
- Hypertension
(84) Prazosin
- Hypertension With BPH
(85) Beta Blockers
- Hypertension with ischemic heart disease.(Angina)
(86) ACE inhibitors
- Hypertension with chronic kidney diseases.
(87) Alpha methylDopa
- Hypertension in pregnancy
(88) Phentolamine
- Hypertensive emergencies with cheese reaction
(89) Nitroprusside+Esmolol
- Hypertensive emergencies in aortic dissection.
(90) Labetalol
- Hypertensive emergencies in pregnancy.
Drugs of choice in shock
(91) Adrenaline
- Anaphylactic shock
(92) Dopamine or noradrenaline
- Cardiogenic shock
(93) Phenylephrine
- Distributive shock
(94) Prazosin
- Secondary shock
(95) Dopamine
- Shock with oliguria
(96) Corticosteroids
- Shock due to adrenal insufficiency
Drugs of choice For viral diseases
(97) Ribavirin
- Viral hemorrhagic fever
- Measles
- Respiratory syncytial virus(in high-risk patient
(98) Zanamivir
- Oseltamivir-resistant influenza
- Oseltamivir
- Seasonal influenza and avian influenza (bird flu)
(99) Acyclovir
- Herpes simplex and varicella.
- Valacyclovir
- Acute herpes zoster.
(100) Gancyclovir
- Cytomegalovirus retinitis.
